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Characterizing thermal transitions of IgG with mass spectrometry
Variable temperature electrospray ionization (ESI) is coupled with mass spectrometry techniques in order to investigate structural transitions of monoclonal antibody immunoglobulin G (IgG) in a 100 mM ammonium acetate (pH 7.0) solution from 26 to 70 °C. At 26 °C, the mass spectrum for intact IgG sho...
Gardado en:
| Publicado en: | J Am Soc Mass Spectrom |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6866664/ https://ncbi.nlm.nih.gov/pubmed/31363989 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13361-019-02292-6 |
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