Mutant-allele tumor heterogeneity in malignant glioma effectively predicts neoplastic recurrence

Intra-tumor heterogeneity (ITH) is one of the most important causes of therapy resistance, which eventually leads to the poor outcomes observed in patients with glioma. Mutant-allele tumor heterogeneity (MATH) values are based on whole-exon sequencing and precisely reflect genetic ITH. However, the...

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Pubblicato in:Oncol Lett
Autori principali: Wu, Pengfei, Yang, Wei, Ma, Jianxing, Zhang, Jingyu, Liao, Maojun, Xu, Lunshan, Xu, Minhui, Yi, Liang
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2019
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6865645/
https://ncbi.nlm.nih.gov/pubmed/31788085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10978
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