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Mutant-allele tumor heterogeneity in malignant glioma effectively predicts neoplastic recurrence
Intra-tumor heterogeneity (ITH) is one of the most important causes of therapy resistance, which eventually leads to the poor outcomes observed in patients with glioma. Mutant-allele tumor heterogeneity (MATH) values are based on whole-exon sequencing and precisely reflect genetic ITH. However, the...
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| Опубликовано в: : | Oncol Lett |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
D.A. Spandidos
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6865645/ https://ncbi.nlm.nih.gov/pubmed/31788085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10978 |
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