A subset of patients with MSS/MSI-low-colorectal cancer showed increased CD8(+) TILs together with up-regulated IFN-γ

A small subset of patients with proficient mismatch repair (pMMR)/microsatellite stable (MSS)-colorectal cancer (CRC) benefit from immunotherapy with anti-programmed cell death 1 (PD-1)/programmed death ligand 1 (PD-L1) blockade. Therefore, the aim of the current study was to evaluate the immune sta...

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Pubblicato in:Oncol Lett
Autori principali: Kikuchi, Tomohiro, Mimura, Kosaku, Okayama, Hirokazu, Nakayama, Yuko, Saito, Katsuharu, Yamada, Leo, Endo, Eisei, Sakamoto, Wataru, Fujita, Shotaro, Endo, Hisahito, Saito, Motonobu, Momma, Tomoyuki, Saze, Zenichiro, Ohki, Shinji, Kono, Koji
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2019
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6865144/
https://ncbi.nlm.nih.gov/pubmed/31788072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2019.10953
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