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Discovery of Novel µ-Opioid Receptor Inverse Agonist from a Combinatorial Library of Tetrapeptides through Structure-Based Virtual Screening

Morphine, oxycodone, fentanyl, and other µ-opioid receptors (MOR) agonists have been used for decades in antinociceptive therapies. However, these drugs are associated with numerous side effects, such as euphoria, addiction, respiratory depression, and adverse gastrointestinal reactions, thus, circu...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Molecules
मुख्य लेखकों: Poli, Giulio, Dimmito, Marilisa Pia, Mollica, Adriano, Zengin, Gokhan, Benyhe, Sandor, Zador, Ferenc, Stefanucci, Azzurra
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6865014/
https://ncbi.nlm.nih.gov/pubmed/31717871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24213872
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