Paradoxical clade- and age-specific vaccine effectiveness during the 2018/19 influenza A(H3N2) epidemic in Canada: potential imprint-regulated effect of vaccine (I-REV)

INTRODUCTION: The Canadian Sentinel Practitioner Surveillance Network reports vaccine effectiveness (VE) for the 2018/19 influenza A(H3N2) epidemic. AIM: To explain a paradoxical signal of increased clade 3C.3a risk among 35–54-year-old vaccinees, we hypothesise childhood immunological imprinting an...

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Dettagli Bibliografici
Pubblicato in:Euro Surveill
Autori principali: Skowronski, Danuta M, Sabaiduc, Suzana, Leir, Siobhan, Rose, Caren, Zou, Macy, Murti, Michelle, Dickinson, James A, Olsha, Romy, Gubbay, Jonathan B, Croxen, Matthew A, Charest, Hugues, Bastien, Nathalie, Li, Yan, Jassem, Agatha, Krajden, Mel, De Serres, Gaston
Natura: Artigo
Lingua:Inglês
Pubblicazione: European Centre for Disease Prevention and Control (ECDC) 2019
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6864978/
https://ncbi.nlm.nih.gov/pubmed/31771709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2807/1560-7917.ES.2019.24.46.1900585
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