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Paradoxical clade- and age-specific vaccine effectiveness during the 2018/19 influenza A(H3N2) epidemic in Canada: potential imprint-regulated effect of vaccine (I-REV)

INTRODUCTION: The Canadian Sentinel Practitioner Surveillance Network reports vaccine effectiveness (VE) for the 2018/19 influenza A(H3N2) epidemic. AIM: To explain a paradoxical signal of increased clade 3C.3a risk among 35–54-year-old vaccinees, we hypothesise childhood immunological imprinting an...

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Detalhes bibliográficos
Publicado no:Euro Surveill
Main Authors: Skowronski, Danuta M, Sabaiduc, Suzana, Leir, Siobhan, Rose, Caren, Zou, Macy, Murti, Michelle, Dickinson, James A, Olsha, Romy, Gubbay, Jonathan B, Croxen, Matthew A, Charest, Hugues, Bastien, Nathalie, Li, Yan, Jassem, Agatha, Krajden, Mel, De Serres, Gaston
Formato: Artigo
Idioma:Inglês
Publicado em: European Centre for Disease Prevention and Control (ECDC) 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6864978/
https://ncbi.nlm.nih.gov/pubmed/31771709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2807/1560-7917.ES.2019.24.46.1900585
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