Prediction of Severity of Drug-Drug Interactions Caused by Enzyme Inhibition and Activation

Drug-drug interactions (DDIs) severity assessment is a crucial problem because polypharmacy is increasingly common in modern medical practice. Many DDIs are caused by alterations of the plasma concentrations of one drug due to another drug inhibiting and/or inducing the metabolism or transporter-med...

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Publicado en:Molecules
Main Authors: Dmitriev, Alexander, Filimonov, Dmitry, Lagunin, Alexey, Karasev, Dmitry, Pogodin, Pavel, Rudik, Anastasiya, Poroikov, Vladimir
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6864873/
https://ncbi.nlm.nih.gov/pubmed/31683720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24213955
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