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Assessment of the cardiovascular adverse effects of drug-drug interactions through a combined analysis of spontaneous reports and predicted drug-target interactions

Adverse drug effects (ADEs) are one of the leading causes of death in developed countries and are the main reason for drug recalls from the market, whereas the ADEs that are associated with action on the cardiovascular system are the most dangerous and widespread. The treatment of human diseases oft...

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Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Ivanov, Sergey, Lagunin, Alexey, Filimonov, Dmitry, Poroikov, Vladimir
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668846/
https://ncbi.nlm.nih.gov/pubmed/31323029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006851
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