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Assessment of the cardiovascular adverse effects of drug-drug interactions through a combined analysis of spontaneous reports and predicted drug-target interactions

Adverse drug effects (ADEs) are one of the leading causes of death in developed countries and are the main reason for drug recalls from the market, whereas the ADEs that are associated with action on the cardiovascular system are the most dangerous and widespread. The treatment of human diseases oft...

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Publicado en:PLoS Comput Biol
Main Authors: Ivanov, Sergey, Lagunin, Alexey, Filimonov, Dmitry, Poroikov, Vladimir
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6668846/
https://ncbi.nlm.nih.gov/pubmed/31323029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006851
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