Synthetic, Structural, and Anticancer Activity Evaluation Studies on Novel Pyrazolylnucleosides

The synthesis of novel pyrazolylnucleosides 3a–e, 4a–e, 5a–e, and 6a–e are described. The structures of the regioisomers were elucidated by using extensive NMR studies. The pyrazolylnucleosides 5a–e and 6a–e were screened for anticancer activities on sixty human tumor cell lines. The compound 6e sho...

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Опубликовано в: :Molecules
Главные авторы: Yadav, Yogesh, Sharma, Deepti, Kaushik, Kumar, Kumar, Vineet, Jha, Amitabh, Prasad, Ashok K., Len, Christophe, Malhotra, Sanjay V., Wengel, Jesper, Parmar, Virinder S.
Формат: Artigo
Язык:Inglês
Опубликовано: MDPI 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6864788/
https://ncbi.nlm.nih.gov/pubmed/31671703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24213922
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