Synthetic, Structural, and Anticancer Activity Evaluation Studies on Novel Pyrazolylnucleosides

The synthesis of novel pyrazolylnucleosides 3a–e, 4a–e, 5a–e, and 6a–e are described. The structures of the regioisomers were elucidated by using extensive NMR studies. The pyrazolylnucleosides 5a–e and 6a–e were screened for anticancer activities on sixty human tumor cell lines. The compound 6e sho...

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Détails bibliographiques
Publié dans:Molecules
Auteurs principaux: Yadav, Yogesh, Sharma, Deepti, Kaushik, Kumar, Kumar, Vineet, Jha, Amitabh, Prasad, Ashok K., Len, Christophe, Malhotra, Sanjay V., Wengel, Jesper, Parmar, Virinder S.
Format: Artigo
Langue:Inglês
Publié: MDPI 2019
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6864788/
https://ncbi.nlm.nih.gov/pubmed/31671703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24213922
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