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Mechanism of Action of Non-Synonymous Single Nucleotide Variations Associated with α-Carbonic Anhydrase II Deficiency

Human carbonic anhydrase II (CA-II) is a Zinc (Zn [Formula: see text]) metalloenzyme responsible for maintenance of acid-base balance within the body through the reversible hydration of CO [Formula: see text] to produce protons (H [Formula: see text]) and bicarbonate (BCT). Due to its importance, al...

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Pubblicato in:Molecules
Autori principali: Sanyanga, Taremekedzwa Allan, Nizami, Bilal, Tastan Bishop, Özlem
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6864701/
https://ncbi.nlm.nih.gov/pubmed/31690045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules24213987
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