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Phorate triggers oxidative stress and mitochondrial dysfunction to enhance micronuclei generation and DNA damage in human lymphocytes

Herein, we studied phorate for its toxicological effects in human lymphocytes. Phorate treatment for 3 h has induced significant increase in the lymphocytic DNA damage. Compared to control, comet data from highest concentration of phorate (1000 µM) showed 8.03-fold increase in the Olive tail moment...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Saudi J Biol Sci
Prif Awduron: Saquib, Quaiser, Faisal, Mohammad, Ansari, Sabiha Mahmood, Wahab, Rizwan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6864401/
https://ncbi.nlm.nih.gov/pubmed/31762602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sjbs.2019.04.008
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