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Phorate triggers oxidative stress and mitochondrial dysfunction to enhance micronuclei generation and DNA damage in human lymphocytes

Herein, we studied phorate for its toxicological effects in human lymphocytes. Phorate treatment for 3 h has induced significant increase in the lymphocytic DNA damage. Compared to control, comet data from highest concentration of phorate (1000 µM) showed 8.03-fold increase in the Olive tail moment...

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Detalhes bibliográficos
Publicado no:Saudi J Biol Sci
Main Authors: Saquib, Quaiser, Faisal, Mohammad, Ansari, Sabiha Mahmood, Wahab, Rizwan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6864401/
https://ncbi.nlm.nih.gov/pubmed/31762602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sjbs.2019.04.008
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