STAT3-induced Wnt5a provides chronic lymphocytic leukemia cells with survival advantage

The wingless and integration site growth factor-5a (Wnt5a) is a ligand of the receptor tyrosine kinase-like orphan receptor-1 (ROR1). Since both Wnt5a and ROR1 are expressed in circulating chronic lymphocytic leukemia (CLL) cells and because in other cell types STAT3, which is constitutively activat...

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Publicado en:J Immunol
Main Authors: Rozovski, Uri, Harris, David M., Li, Ping, Liu, Zhiming, Jain, Preetesh, Ferrajoli, Alessandra, Burger, Jan A., Bose, Prithviraj, Thompson, Phillip A., Jain, Nitin, Wierda, William G., Uziel, Orit, Keating, Michael J., Estrov, Zeev
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6864283/
https://ncbi.nlm.nih.gov/pubmed/31645416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900389
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