STAT3-induced Wnt5a provides chronic lymphocytic leukemia cells with survival advantage

The wingless and integration site growth factor-5a (Wnt5a) is a ligand of the receptor tyrosine kinase-like orphan receptor-1 (ROR1). Since both Wnt5a and ROR1 are expressed in circulating chronic lymphocytic leukemia (CLL) cells and because in other cell types STAT3, which is constitutively activat...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Rozovski, Uri, Harris, David M., Li, Ping, Liu, Zhiming, Jain, Preetesh, Ferrajoli, Alessandra, Burger, Jan A., Bose, Prithviraj, Thompson, Phillip A., Jain, Nitin, Wierda, William G., Uziel, Orit, Keating, Michael J., Estrov, Zeev
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6864283/
https://ncbi.nlm.nih.gov/pubmed/31645416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900389
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