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Imidazole Derivatives Improve Charge Reduction and Stabilization for Native Mass Spectrometry

Noncovalent interactions between biomolecules are critical to their activity. Native mass spectrometry (MS) has enabled characterization of these interactions by preserving noncovalent assemblies for mass analysis, including protein-ligand and protein-protein complexes for a wide range of soluble an...

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Bibliographic Details
Published in:Anal Chem
Main Authors: Townsend, Julia A., Keener, James E., Miller, Zachary M., Prell, James S., Marty, Michael T.
Format: Artigo
Language:Inglês
Published: 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6864253/
https://ncbi.nlm.nih.gov/pubmed/31638377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.9b04263
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