A Novel Fully-Human Potency-Matched Dual Cytokine-Antibody Fusion Protein Targets Carbonic Anhydrase IX in Renal Cell Carcinomas

Certain cytokines synergize in activating anti-cancer immunity at the site of disease and it may be desirable to generate biopharmaceutical agents, capable of simultaneous delivery of cytokine pairs to the tumor. In this article, we have described the cloning, expression and characterization of IL2-...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: De Luca, Roberto, Gouyou, Baptiste, Ongaro, Tiziano, Villa, Alessandra, Ziffels, Barbara, Sannino, Alessandro, Buttinoni, Gianluca, Galeazzi, Simone, Mazzacuva, Mirko, Neri, Dario
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6863974/
https://ncbi.nlm.nih.gov/pubmed/31799191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.01228
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