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Guide to Virtual Screening: Application to the Akt Phosphatase PHLPP
We present an example-based description of virtual screening (VS) techniques used to identify new regulators of the Akt phosphatase PHLPP (PH domain Leucine-rich repeat Protein Phosphatase). This enzyme opposes the effects of two kinases, Akt and PKC, which play a major role in cell growth and survi...
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| Udgivet i: | Methods Mol Biol |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6863617/ https://ncbi.nlm.nih.gov/pubmed/22183558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-61779-465-0_33 |
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