Role of the Autotaxin-Lysophosphatidic acid axis in glaucoma, aqueous humor drainage and fibrogenic activity

Ocular hypertension due to impaired aqueous humor (AH) drainage through the trabecular meshwork (TM) is a major risk factor for glaucoma, a leading cause of irreversible blindness. However, the etiology of ocular hypertension remains unclear. Although autotaxin, a secreted lysophospholipase D and it...

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Publicado en:Biochim Biophys Acta Mol Basis Dis
Autores principales: Ho, Leona T. Y., Osterwald, Anja, Ruf, Iris, Hunziker, Daniel, Mattei, Patrizio, Challa, Pratap, Vann, Robin, Ullmer, Christoph, Vasanth Rao, Ponugoti
Formato: Artigo
Lenguaje:Inglês
Publicado: 2019
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6863611/
https://ncbi.nlm.nih.gov/pubmed/31648019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2019.165560
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