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Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells
The age-related failure to produce oligodendrocytes from oligodendrocyte progenitor cells (OPCs) is associated with irreversible neurodegeneration in multiple sclerosis (MS). Consequently, regenerative approaches have significant potential for treating chronic demyelinating diseases. Here, we show t...
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| Pubblicato in: | Cell Stem Cell |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cell Press
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6863391/ https://ncbi.nlm.nih.gov/pubmed/31585093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2019.08.015 |
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