Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells

The age-related failure to produce oligodendrocytes from oligodendrocyte progenitor cells (OPCs) is associated with irreversible neurodegeneration in multiple sclerosis (MS). Consequently, regenerative approaches have significant potential for treating chronic demyelinating diseases. Here, we show t...

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Publicat a:Cell Stem Cell
Autors principals: Neumann, Björn, Baror, Roey, Zhao, Chao, Segel, Michael, Dietmann, Sabine, Rawji, Khalil S., Foerster, Sarah, McClain, Crystal R., Chalut, Kevin, van Wijngaarden, Peter, Franklin, Robin J.M.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6863391/
https://ncbi.nlm.nih.gov/pubmed/31585093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2019.08.015
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