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The oncogene Gankyrin is expressed in testicular cancer and contributes to cisplatin sensitivity in embryonal carcinoma cells
BACKGROUND: Testicular germ cell cancer (TGCC) develops from pre-malignant germ neoplasia in situ (GCNIS) cells. GCNIS originates from fetal gonocytes (POU5F1(+)/MAGE-A4(−)), which fail to differentiate to pre-spermatogonia (POU5F1(−)/MAGE-A4(+)) and undergo malignant transformation. Gankyrin is an...
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| Gepubliceerd in: | BMC Cancer |
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| Hoofdauteurs: | , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
BioMed Central
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6862764/ https://ncbi.nlm.nih.gov/pubmed/31744479 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-6340-7 |
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