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Concurrent genome and epigenome editing by CRISPR-mediated sequence replacement
BACKGROUND: Recent advances in genome editing have facilitated the direct manipulation of not only the genome, but also the epigenome. Genome editing is typically performed by introducing a single CRISPR/Cas9-mediated double-strand break (DSB), followed by non-homologous end joining (NHEJ)- or homol...
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| Udgivet i: | BMC Biol |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6862751/ https://ncbi.nlm.nih.gov/pubmed/31739790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-019-0711-z |
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