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Diazotization of S-Sulfonyl-cysteines

[Image: see text] We report the preparation of enantiomerically enriched β-thio-α-hydroxy and α-chloro carboxylic acid and ester building blocks by diazotization of S-sulfonyl-cysteines. The thiosulfonate protecting group demonstrated resistance to oxidation and attenuation of sulfur’s nucleophilici...

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Detalhes bibliográficos
Publicado no:J Org Chem
Main Authors: Mear, Sarah Jane, Jamison, Timothy F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2019
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6862327/
https://ncbi.nlm.nih.gov/pubmed/31657562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.9b02630
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