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Independent and Combined Effects of Telomere Shortening and mtDNA(4977) Deletion on Long-term Outcomes of Patients with Coronary Artery Disease

Aging is one of the main risk factors for cardiovascular disease, resulting in a progressive organ and cell decline. This study evaluated a possible joint impact of two emerging hallmarks of aging, leucocyte telomere length (LTL) and common mitochondrial DNA deletion (mtDNA(4977)), on major adverse...

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Pubblicato in:Int J Mol Sci
Autori principali: Vecoli, Cecilia, Borghini, Andrea, Pulignani, Silvia, Mercuri, Antonella, Turchi, Stefano, Picano, Eugenio, Andreassi, Maria Grazia
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6862167/
https://ncbi.nlm.nih.gov/pubmed/31694204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20215508
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