ATRX Contributes to MeCP2-Mediated Pericentric Heterochromatin Organization during Neural Differentiation

Methyl-CpG binding protein 2 (MeCP2) is a multi-function factor involved in locus-specific transcriptional modulation and the regulation of genome architecture, e.g., pericentric heterochromatin (PCH) organization. MECP2 mutations are responsible for Rett syndrome (RTT), a devastating postnatal neur...

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Publicat a:Int J Mol Sci
Autors principals: Marano, Domenico, Fioriniello, Salvatore, Fiorillo, Francesca, Gibbons, Richard J., D’Esposito, Maurizio, Della Ragione, Floriana
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6862095/
https://ncbi.nlm.nih.gov/pubmed/31671722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20215371
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