Repeated Vaginal Exposures to the Common Cosmetic and Household Preservative Methylisothiazolinone Induce Persistent, Mast Cell-Dependent Genital Pain in ND4 Mice

A history of allergies doubles the risk of vulvodynia—a chronic pain condition of unknown etiology often accompanied by increases in numbers of vulvar mast cells. We previously established the biological plausibility of this relationship in mouse models where repeated exposures to the allergens oxaz...

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Udgivet i:Int J Mol Sci
Main Authors: Arriaga-Gomez, Erica, Kline, Jaclyn, Emanuel, Elizabeth, Neamonitaki, Nefeli, Yangdon, Tenzin, Zacheis, Hayley, Pasha, Dogukan, Lim, Jinyoung, Bush, Susan, Boo, Beebie, Mengistu, Hanna, Kinnamon, Ruby, Shields-Cutler, Robin, Wattenberg, Elizabeth, Chatterjea, Devavani
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6862067/
https://ncbi.nlm.nih.gov/pubmed/31661848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20215361
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