Cortistatin exerts antiproliferation and antimigration effects in vascular smooth muscle cells stimulated by Ang II through suppressing ERK1/2, p38 MAPK, JNK and ERK5 signaling pathways

BACKGROUND: Vascular remodeling, that contributes to cardiovascular diseases such as hypertension develops by anomalous proliferation and migration of vascular smooth muscle cells (VSMCs). Cortistatin (CST), a newly discovered biological peptide, has been acknowledged for its protective effects agai...

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Bibliographische Detailangaben
Veröffentlicht in:Ann Transl Med
Hauptverfasser: Wang, Ying, Zhang, Xin, Gao, Lei, Li, Jihe, Chen, Wenjia, Chi, Jinyu, Zhang, Xiaohui, Fu, Yu, Zhao, Meng, Liu, Na, Li, Yang, Xu, Yang, Yang, Kelaier, Yin, Xinhua, Liu, Yue
Format: Artigo
Sprache:Inglês
Veröffentlicht: AME Publishing Company 2019
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6861776/
https://ncbi.nlm.nih.gov/pubmed/31807542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2019.09.45
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