Antidepressant-like effects of the Guanxin Danshen formula via mediation of the CaMK II-CREB-BDNF signalling pathway in chronic unpredictable mild stress-induced depressive rats

BACKGROUND: Depression is a chronic and recurrent syndrome of mood disorder causing immense social and economic burden; thus, treatment should be improved. Guanxin Danshen formula (GXDSF), a natural botanical drug composition prescription, has significant cardiovascular protective effects and is wid...

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Bibliographische Detailangaben
Veröffentlicht in:Ann Transl Med
Hauptverfasser: Xie, Weijie, Meng, Xiangbao, Zhai, Yadong, Ye, Tianyuan, Zhou, Ping, Nan, Fengwei, Sun, Guibo, Sun, Xiaobo
Format: Artigo
Sprache:Inglês
Veröffentlicht: AME Publishing Company 2019
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6861747/
https://ncbi.nlm.nih.gov/pubmed/31807545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2019.09.39
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