Notoginsenoside R1 Improves Cerebral Ischemia/Reperfusion Injury by Promoting Neurogenesis via the BDNF/Akt/CREB Pathway

Notoginsenoside R1 (R1), a major component isolated from P. notoginseng, is a phytoestrogen that exerts many neuroprotective effects in a rat model of ischemic stroke. However, its long-term effects on neurogenesis and neurological restoration after ischemic stroke have not been investigated. The ai...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Zhu, Ting, Wang, Lei, Xie, Weijie, Meng, Xiangbao, Feng, Yicheng, Sun, Guibo, Sun, Xiaobo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8138209/
https://ncbi.nlm.nih.gov/pubmed/34025400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.615998
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