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AAV-Anti-miR-214 Prevents Collapse of the Femoral Head in Osteonecrosis by Regulating Osteoblast and Osteoclast Activities

Osteonecrosis of the femoral head, an intractable but common disease that eventually triggers collapse of the femoral head, is characterized by increased osteoclast activity and markedly decreased osteoblast activity in the necrotic region of the femoral head. MicroRNA (miRNA)-214 (miR-214) may play...

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Détails bibliographiques
Publié dans:Mol Ther Nucleic Acids
Auteurs principaux: Wang, Cheng, Sun, Weijia, Ling, Shukuan, Wang, Yu, Wang, Xin, Meng, Haoye, Li, Yuheng, Yuan, Xueling, Li, Jianwei, Liu, Ruoxi, Zhao, Dingsheng, Lu, Qiang, Wang, Aiyuan, Guo, Quanyi, Lu, Shibi, Tian, Hua, Li, Yingxian, Peng, Jiang
Format: Artigo
Langue:Inglês
Publié: American Society of Gene & Cell Therapy 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6861671/
https://ncbi.nlm.nih.gov/pubmed/31739209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.09.030
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