AAV-Anti-miR-214 Prevents Collapse of the Femoral Head in Osteonecrosis by Regulating Osteoblast and Osteoclast Activities

Osteonecrosis of the femoral head, an intractable but common disease that eventually triggers collapse of the femoral head, is characterized by increased osteoclast activity and markedly decreased osteoblast activity in the necrotic region of the femoral head. MicroRNA (miRNA)-214 (miR-214) may play...

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Udgivet i:Mol Ther Nucleic Acids
Main Authors: Wang, Cheng, Sun, Weijia, Ling, Shukuan, Wang, Yu, Wang, Xin, Meng, Haoye, Li, Yuheng, Yuan, Xueling, Li, Jianwei, Liu, Ruoxi, Zhao, Dingsheng, Lu, Qiang, Wang, Aiyuan, Guo, Quanyi, Lu, Shibi, Tian, Hua, Li, Yingxian, Peng, Jiang
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6861671/
https://ncbi.nlm.nih.gov/pubmed/31739209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.09.030
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