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Nrf2 activation in osteoblasts suppresses osteoclastogenesis via inhibiting IL-6 expression.
Bone destructive diseases such as periodontitis and rheumatoid arthritis are caused by excessive activation of osteoclasts. Osteoclastogenesis is regulated by Receptor activator of nuclear factor kappa-β ligand (RANKL) produced by osteoclastogenesis supporting cells such as osteoblast and osteocyte....
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| Publicado no: | Bone Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6861591/ https://ncbi.nlm.nih.gov/pubmed/31763378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bonr.2019.100228 |
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