Dimethyl fumarate inhibits osteoclasts via attenuation of reactive oxygen species signalling by augmented antioxidation

Bone destructive diseases are common worldwide and are caused by dysregulation of osteoclast formation and activation. During osteoclastogenesis, reactive oxygen species (ROS) play a role in the intracellular signalling triggered by receptor activator of nuclear factor‐κB ligand (RANKL) stimulation....

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Yamaguchi, Yuuki, Kanzaki, Hiroyuki, Katsumata, Yuta, Itohiya, Kanako, Fukaya, Sari, Miyamoto, Yutaka, Narimiya, Tsuyoshi, Wada, Satoshi, Nakamura, Yoshiki
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783833/
https://ncbi.nlm.nih.gov/pubmed/29063666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13367
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