Dimethyl fumarate inhibits osteoclasts via attenuation of reactive oxygen species signalling by augmented antioxidation

Bone destructive diseases are common worldwide and are caused by dysregulation of osteoclast formation and activation. During osteoclastogenesis, reactive oxygen species (ROS) play a role in the intracellular signalling triggered by receptor activator of nuclear factor‐κB ligand (RANKL) stimulation....

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Veröffentlicht in:J Cell Mol Med
Hauptverfasser: Yamaguchi, Yuuki, Kanzaki, Hiroyuki, Katsumata, Yuta, Itohiya, Kanako, Fukaya, Sari, Miyamoto, Yutaka, Narimiya, Tsuyoshi, Wada, Satoshi, Nakamura, Yoshiki
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5783833/
https://ncbi.nlm.nih.gov/pubmed/29063666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.13367
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