Size Matters: Arginine-Derived Peptides Targeting the PSMA Receptor Can Efficiently Complex but Not Transfect siRNA

Oligoarginine sequences conjugated to a short cancer-targeting peptide (CTP) selective for the prostate-specific membrane antigen (PSMA) receptor was developed for selective small interfering RNA (siRNA) delivery to a human metastatic/castration-resistant prostate cancer (PCa) cell line, which expre...

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Udgivet i:Mol Ther Nucleic Acids
Main Authors: Cultrara, Christopher N., Shah, Sunil, Antuono, Gina, Heller, Claudia J., Ramos, Jorge A., Samuni, Uri, Zilberberg, Jenny, Sabatino, David
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6861565/
https://ncbi.nlm.nih.gov/pubmed/31739211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2019.10.013
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