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Genetic study in a family with dopa-responsive dystonia revealed a novel mutation in sepiapterin reductase gene

Dopa-responsive dystonia due to sepiapterin reductase deficiency (OMIM#612716) is caused by recessive mutations in the gene encoding sepiapterin reductase (SPR), which plays an important role in the biosynthesis of tetrahydrobiopterin (BH4). One Jordanian patient to first cousin parents is reported...

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Vydáno v:Pak J Med Sci
Hlavní autor: Froukh, Tawfiq
Médium: Artigo
Jazyk:Inglês
Vydáno: Professional Medical Publications 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6861483/
https://ncbi.nlm.nih.gov/pubmed/31777525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12669/pjms.35.6.1181
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