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Phenocopies in a large GCH1 mutation positive family with dopa responsive dystonia: confusing the picture?

Objective: To study a large Canadian family with presumed DRD. Methods: The clinical features of the family were collected before molecular genetic mutational analysis. Results: All nine individuals in whom a clinical diagnosis of DRD was definite or probable were heterozygous for a GCH1 gene deleti...

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Main Authors: Grimes, D, Barclay, C, Duff, J, Furukawa, Y, Lang, A
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Group 2002
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1737930/
https://ncbi.nlm.nih.gov/pubmed/12023430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jnnp.72.6.801
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