Quorum sensing modulates the formation of virulent Legionella persisters within infected cells

The facultative intracellular bacterium Legionella pneumophila replicates in environmental amoebae and in lung macrophages, and causes Legionnaires’ disease. Here we show that L. pneumophila reversibly forms replicating and nonreplicating subpopulations of similar size within amoebae. The nonreplica...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Personnic, Nicolas, Striednig, Bianca, Lezan, Emmanuelle, Manske, Christian, Welin, Amanda, Schmidt, Alexander, Hilbi, Hubert
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6861284/
https://ncbi.nlm.nih.gov/pubmed/31740681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-13021-8
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