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Quantitative Imaging Flow Cytometry of Legionella-Infected Dictyostelium Amoebae Reveals the Impact of Retrograde Trafficking on Pathogen Vacuole Composition

The ubiquitous environmental bacterium Legionella pneumophila survives and replicates within amoebae and human macrophages by forming a Legionella-containing vacuole (LCV). In an intricate process governed by the bacterial Icm/Dot type IV secretion system and a plethora of effector proteins, the nas...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Main Authors: Welin, Amanda, Weber, Stephen, Hilbi, Hubert
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5960973/
https://ncbi.nlm.nih.gov/pubmed/29602783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00158-18
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