Plasma fibroblast growth factor 21 levels increase with ectopic fat accumulation and its receptor levels are decreased in the visceral fat of patients with type 2 diabetes

BACKGROUND: Fibroblast growth factor 21 (FGF21) is a novel metabolic regulator that has beneficial effects on glucose and lipid metabolism. However, plasma FGF21 levels are paradoxically increased in type 2 diabetes mellitus (T2DM) and obesity, suggesting resistance to this ligand. FGF21 acts mainly...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:BMJ Open Diabetes Res Care
Hauptverfasser: Hong, Eun Shil, Lim, Cheong, Choi, Hye Yeon, Lee, Yun Kyung, Ku, Eu Jeong, Moon, Jae Hoon, Park, Kyong Soo, Jang, Hak Chul, Choi, Sung Hee
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMJ Publishing Group 2019
Schlagworte:
Metabolism
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6861080/
https://ncbi.nlm.nih.gov/pubmed/31798902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjdrc-2019-000776
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge