Plasma fibroblast growth factor 21 levels increase with ectopic fat accumulation and its receptor levels are decreased in the visceral fat of patients with type 2 diabetes

BACKGROUND: Fibroblast growth factor 21 (FGF21) is a novel metabolic regulator that has beneficial effects on glucose and lipid metabolism. However, plasma FGF21 levels are paradoxically increased in type 2 diabetes mellitus (T2DM) and obesity, suggesting resistance to this ligand. FGF21 acts mainly...

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Detalhes bibliográficos
Publicado no:BMJ Open Diabetes Res Care
Main Authors: Hong, Eun Shil, Lim, Cheong, Choi, Hye Yeon, Lee, Yun Kyung, Ku, Eu Jeong, Moon, Jae Hoon, Park, Kyong Soo, Jang, Hak Chul, Choi, Sung Hee
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2019
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6861080/
https://ncbi.nlm.nih.gov/pubmed/31798902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjdrc-2019-000776
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