Tanshinone IIA Reverses Oxaliplatin Resistance In Human Colorectal Cancer Via Inhibition Of ERK/Akt Signaling Pathway

BACKGROUND: Oxaliplatin (OXA)-based chemotherapy is generally used to treat human cancers, whereas OXA resistance is a main obstacle for the treatment of colorectal cancer (CRC). Evidence has shown that tanshinone IIA (Tan IIA) could induce apoptosis in CRC cells. However, the role of combination of...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Zhang, Yonggang, Ge, Tingrui, Xiang, Ping, Zhou, Jingyi, Tang, Shumin, Mao, Haibing, Tang, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859961/
https://ncbi.nlm.nih.gov/pubmed/32009805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S217914
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