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Thermodynamic examination of pH and magnesium effect on U6 RNA internal loop

U6 RNA contains a 1 × 2-nt internal loop that folds and unfold during spliceosomal assembly and activation. The 1 × 2 loop consists of a C(67)•A(79) base pair that forms an additional hydrogen bond upon protonation, C(67)•A(+)(79), and uracil (U80) that coordinates the catalytically essential magnes...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: O'Connell, Allison A., Hanson, Jared A., McCaskill, Darryl C., Moore, Ethan T., Lewis, Daniel C., Grover, Neena
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859860/
https://ncbi.nlm.nih.gov/pubmed/31548339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.070466.119
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