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Enhanced Keap1-Nrf2 signaling protects the myocardium from isoproterenol-induced pathological remodeling in mice

Nuclear factor (erythroid-derived 2)-like 2 (NFE2L2/Nrf2) is an inducible transcription factor that is essential for maintenance of redox signaling in response to stress. This suggests that if Nrf2 expression response could be enhanced for a defined physiological pro-oxidant stress then it would be...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Shanmugam, Gobinath, Challa, Anil Kumar, Litovsky, Silvio H., Devarajan, Asokan, Wang, Ding, Jones, Dean P., Darley-Usmar, Victor M., Rajasekaran, Namakkal Soorappan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859568/
https://ncbi.nlm.nih.gov/pubmed/31155513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101212
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