Ku80 promotes melanoma growth and regulates antitumor effect of melatonin by targeting HIF1-α dependent PDK-1 signaling pathway

Melanoma is one of the most malignant and aggressive cancers with high cancer-related deaths. However, it is unclear whether Ku80 regulates tumor growth in human melanoma. In this study, we screened a siRNA library targeting 6024 human genes and identified Ku80 as a potential therapeutic target in m...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Redox Biol
Glavni autori: Liu, Tianze, Jin, Lizi, Chen, Miao, Zheng, Zongheng, Lu, Wenjing, Fan, Wenhua, Li, Liren, Zheng, Fufu, Zhu, Qiaohua, Qiu, Huijuan, Liu, Jiani, Chen, Manyu, Tian, Chunfang, Hu, Zheng, Zhang, Changlin, Luo, Meihua, Li, Jian, Kang, Tiebang, Yang, Lukun, Li, Yizhuo, Deng, Wuguo
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2019
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859552/
https://ncbi.nlm.nih.gov/pubmed/31023624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101197
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items