EZH2 Contributes To Cisplatin Resistance In Breast Cancer By Epigenetically Suppressing miR-381 Expression

BACKGROUND: Emerging evidence reveals the vital role of enhancer of zeste homolog 2 (EZH2) in cancer chemoresistance. However, its function and molecular mechanisms in breast cancer chemoresistance remain largely unknown. METHODS: Gene expression was evaluated using quantitative real-time PCR (qRT-P...

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Detalles Bibliográficos
Publicado en:Onco Targets Ther
Main Authors: Dou, Dongwei, Ge, Xin, Wang, Xinxing, Xu, Xiaodong, Zhang, Zhe, Seng, Jingjing, Cao, Zhang, Gu, Yuanting, Han, Mingli
Formato: Artigo
Idioma:Inglês
Publicado: Dove 2019
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Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6859472/
https://ncbi.nlm.nih.gov/pubmed/32009798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S214104
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