Cancer-Associated Fibroblasts-Derived Exosomes Suppress Immune Cell Function in Breast Cancer via the miR-92/PD-L1 Pathway

Cancer-associated fibroblasts (CAFs) are an essential component in the tumor microenvironment and have been reported to contribute to tumor progression through many mechanisms; however, the detailed mechanism underlying the immune-suppression effect of CAFs is not clearly defined. In this study, hum...

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Detalles Bibliográficos
Publicado en:Front Immunol
Main Authors: Dou, Dongwei, Ren, Xiaoyang, Han, Mingli, Xu, Xiaodong, Ge, Xin, Gu, Yuanting, Wang, Xinxing
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Immunology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7581790/
https://ncbi.nlm.nih.gov/pubmed/33162971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.02026
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