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Directing differentiation of human induced pluripotent stem cells toward androgen-producing Leydig cells rather than adrenal cells
Reduced serum testosterone (T), or hypogonadism, affects millions of men and is associated with many pathologies, including infertility, cardiovascular diseases, metabolic syndrome, and decreased libido and sexual function. Administering T-replacement therapy (TRT) reverses many of the symptoms asso...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6859353/ https://ncbi.nlm.nih.gov/pubmed/31591190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1908207116 |
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