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Quantifying the impact of treatment history on plasmid-mediated resistance evolution in human gut microbiota
To understand how antibiotic use affects the risk of a resistant infection, we present a computational model of the population dynamics of gut microbiota including antibiotic resistance-conferring plasmids. We then describe how this model is parameterized based on published microbiota data. Finally,...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6859334/ https://ncbi.nlm.nih.gov/pubmed/31666328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1912188116 |
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